| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1841 | |
| Phytochemical name or plant extracts | Coptisine | |
| PMID | 25081696 | |
| Literature evidence | Coptisine might be a potential drug candidate for breast cancer therapy. | |
| IUPAC name | 5,7,17,19-tetraoxa-13-azoniahexacyclo[11.11.0.02,10.04,8.015,23.016,20]tetracosa-1(13),2,4(8),9,14,16(20),21,23-octaene | |
| Phytochemicals’ class or type of plant extracts | Alkaloid | |
| Source of phytochemicals or plant Extracts | Coptidis rhizoma | |
| Geographical availability | NA | |
| Plant parts | NA | |
| Other cancers | Breast cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | Coptisine might be a potential drug candidate for breast cancer therapy. | |
| Cell line/ mice model | MDA-MB-231 | |
| Additional information | coptisine efficiently suppressed the adhesion, migration and invasion of human breast cancer MDA-MB-231 cells accompanied with the interference to the expression of MMP-9 and its specific inhibitor TIMP-1. | |
| PubChem ID | 72322 | |
| Additional PMIDs | NA | |
| Additional sources of information | NA | |
| Safety | NA |