| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1710 | |
| Phytochemical name or plant extracts | Coleus hybridus extract | |
| PMID | 32188380 | |
| Literature evidence | DISCUSSION: At a low concentration of 10 μg/mL, C. hybridus calli and seedling extracts showed the most significant anti-proliferative effects after 24 and 48 h of exposure (p < 0.01), controls (doxorubicin) also showed significant inhibition, but lesser than that observed with C. hybridus (p < 0.05). | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Methanolic crude extract | |
| Source of phytochemicals or plant Extracts | Coleus hybridus | |
| Geographical availability | Bismarck Archipelago, Borneo, Cambodia, China Southeast, Jawa, Laos, Lesser Sunda Is., Malaya, Maluku, Myanmar, Nansei-shoto, New Guinea, Northern Territory, Philippines, Queensland, Solomon Is., Sulawesi, Sumatera, Taiwan, Thailand, Vanuatu, Vietnam, Western Australia | |
| Plant parts | Seedsling | |
| Other cancers | Breast cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | Methanolic extracts of R. officinalis and C. hybridus are potentially valuable options for breast cancer treatment. | |
| Cell line/ mice model | MCF-7 | |
| Additional information | Shows anti-proliferative effects against MCF-7 cells | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:446027-1 | |
| Safety | NA |