| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1761 | |
| Phytochemical name or plant extracts | Coffee extract | |
| PMID | 21963506 | |
| Literature evidence | Coffee treatment of Caco-2 cells also increased the level of BCRP protein, which corresponded to induction of gene expression, and also increased cellular efflux activity, as judged by Hoechst33342 accumulation. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Extract | |
| Source of phytochemicals or plant Extracts | Coffea arabica | |
| Geographical availability | Ethiopia, Kenya, Sudan | |
| Plant parts | NA | |
| Other cancers | Breast cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | Coffee induces breast cancer resistance protein expression in Caco-2 cells | |
| Cell line/ mice model | MDA-MB-231, MCF-7 | |
| Additional information | Coffee shows protective effects against the action of specific carcinogens such as PhIP and nitrosoamines. | |
| PubChem ID | 6850756 | |
| Additional PMIDs | NA | |
| Additional sources of information | NA | |
| Safety | NA |