| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-2111 | |
| Phytochemical name or plant extracts | Coclaurine | |
| PMID | 31384762 | |
| Literature evidence | One of these alkaloids, 6, 7-dimethoxy-1-(α-hydroxy-4-methoxybenzyl)-2-methyl-1, 2, 3, 4-tetrahydroisoquinoline, was isolated for the first time from natural sources, while, the alkaloid, Coclaurine was known in Annona squamosa L. | |
| IUPAC name | (1S)-1-[(4-hydroxyphenyl)methyl]-6-methoxy-1,2,3,4-tetrahydroisoquinolin-7-ol | |
| Phytochemicals’ class or type of plant extracts | Alkaloid | |
| Source of phytochemicals or plant Extracts | Annona squamosa | |
| Geographical availability | Belize, Colombia, Costa Rica, El Salvador, Guatemala, Honduras, Mexico Central, Mexico Gulf, Mexico Northeast, Mexico Northwest, Mexico Southeast, Mexico Southwest, Nicaragua, Panamá | |
| Plant parts | Aerial parts | |
| Other cancers | Breast cancer, Colon cancer, Liver cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 15.345 µg/mL against MCF-7 | |
| Potency | NA | |
| Cell line/ mice model | HepG-2, MCF-7, HCT-116 | |
| Additional information | NA | |
| PubChem ID | 160487 | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:72319-1 | |
| Safety | NA |