| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-748 | |
| Phytochemical name or plant extracts | Cleistochlamys kirkii extract | |
| PMID | 31362371 | |
| Literature evidence | Our findings demonstrate the potential applicability of C. kirkii as a source of antimalarial and anticancer agents. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Crude extract | |
| Source of phytochemicals or plant Extracts | Cleistochlamys kirkii | |
| Geographical availability | Malawi, Mozambique, Tanzania, Zambia, Zimbabwe | |
| Plant parts | Root | |
| Other cancers | Breast cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 42.0 μg/mL against MDA-MB-231 | |
| Potency | This indicates the potential applicability of C. kirkii as a source of antimalarial, and even more likely of anticancer agents. | |
| Cell line/ mice model | MDA-MB-231 | |
| Additional information | The ethanolic crude extract of C. kirkii root bark gave 72% inhibition against the chloroquine-sensitive 3D7-strain malaria parasite Plasmodium falciparum at 0.01 µg/mL. | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:72604-1 | |
| Safety | NA |