Phytochemical Name : Clausenalansimin A

Properties Information
PhytoCAT-ID PhytoCAT-1523
Phytochemical name or plant extracts Clausenalansimin A
PMID 28826247
Literature evidence Compounds 1-8 exhibited significant inhibitory effects with IC50 values ranging from 1.36 to 18.96 μM.
IUPAC name 9-{[(2E,5S)-5-hydroxy-3,7-dimethylocta-2,6-dien-1-yl]oxy}-7H-furo[3,2-g]chromen-7-one
Phytochemicals’ class or type of plant extracts Furanocoumarin
Source of phytochemicals or plant Extracts Clausena hainanensis
Geographical availability Hainan
Plant parts Leaves and stem
Other cancers Breast cancer, Leukemia, Liver cancer, Lung cancer, Colon cancer
Target gene or protein NA
Gene or Protein evidence NA
Target pathways NA
IC50 8.42 ± 0.08 µM against MCF-7
Potency The cytotoxicities against several human cancer cell lines of 1–8 were also investigated, and found to be quite potent, which may be used as an explanation of the folk use of C. hainanensis, which had been used to treat tumours in China
Cell line/ mice model HL-60, SMMC-7721, A-549, MCF-7 and SW480
Additional information  NA
PubChem ID NA
Additional PMIDs NA
Additional sources of information https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:961410-1
Safety NA