Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-1523 | |
Phytochemical name or plant extracts | Clausenalansimin A | |
PMID | 28826247 | |
Literature evidence | Compounds 1-8 exhibited significant inhibitory effects with IC50 values ranging from 1.36 to 18.96 μM. | |
IUPAC name | 9-{[(2E,5S)-5-hydroxy-3,7-dimethylocta-2,6-dien-1-yl]oxy}-7H-furo[3,2-g]chromen-7-one | |
Phytochemicals’ class or type of plant extracts | Furanocoumarin | |
Source of phytochemicals or plant Extracts | Clausena hainanensis | |
Geographical availability | Hainan | |
Plant parts | Leaves and stem | |
Other cancers | Breast cancer, Leukemia, Liver cancer, Lung cancer, Colon cancer | |
Target gene or protein | NA | |
Gene or Protein evidence | NA | |
Target pathways | NA | |
IC50 | 8.42 ± 0.08 µM against MCF-7 | |
Potency | The cytotoxicities against several human cancer cell lines of 1–8 were also investigated, and found to be quite potent, which may be used as an explanation of the folk use of C. hainanensis, which had been used to treat tumours in China | |
Cell line/ mice model | HL-60, SMMC-7721, A-549, MCF-7 and SW480 | |
Additional information | NA | |
PubChem ID | NA | |
Additional PMIDs | NA | |
Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:961410-1 | |
Safety | NA |