Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-1225 | |
Phytochemical name or plant extracts | Clausena excavata stem bark extract | |
PMID | 23178663 | |
Literature evidence | Acridine orange/propidium iodide staining was used to detect cells in early apoptosis and high content screening (HCS) to observe nuclear condensation, cell permeability, mitochondrial membrane potential (MMP) and cytochrome c release. | |
IUPAC name | NA | |
Phytochemicals’ class or type of plant extracts | Hexane, Chloroform,ethyl acetate and MeOH extract | |
Source of phytochemicals or plant Extracts | Clausena excavata Burm | |
Geographical availability | Assam, Bangladesh, Borneo, Cambodia, China South-Central, China Southeast, East Himalaya, Hainan, India, Jawa, Laos, Lesser Sunda Is., Malaya, Myanmar, Nepal, New Guinea, Philippines, Sulawesi, Sumatera, Taiwan, Thailand, Vietnam | |
Plant parts | Stem | |
Other cancers | Breast cancer, Liver cancer, Cervical cancer, Colorectal cancer | |
Target gene or protein | NA | |
Gene or Protein evidence | NA | |
Target pathways | NA | |
IC50 | Hexane extract - 12.88±0.45 µg/ml against MCF-7 Ethyl acetate extract - 18.07±1.60 µg/ml against MCF-7 Chloroform extract - 27.06±1.67 µg/ml against MCF-7 Methanol extract - 23.43±1.80 µg/ml against MCF-7 | |
Potency | NA | |
Cell line/ mice model | NA | |
Additional information | NA | |
PubChem ID | NA | |
Additional PMIDs | NA | |
Additional sources of information | NA | |
Safety | NA |