Phytochemical Name : Clausena excavata stem bark extract

Properties Information
PhytoCAT-ID PhytoCAT-1225
Phytochemical name or plant extracts Clausena excavata stem bark extract
PMID 23178663
Literature evidence Acridine orange/propidium iodide staining was used to detect cells in early apoptosis and high content screening (HCS) to observe nuclear condensation, cell permeability, mitochondrial membrane potential (MMP) and cytochrome c release.
IUPAC name NA
Phytochemicals’ class or type of plant extracts Hexane, Chloroform,ethyl acetate and MeOH extract
Source of phytochemicals or plant Extracts Clausena excavata Burm
Geographical availability Assam, Bangladesh, Borneo, Cambodia, China South-Central, China Southeast, East Himalaya, Hainan, India, Jawa, Laos, Lesser Sunda Is., Malaya, Myanmar, Nepal, New Guinea, Philippines, Sulawesi, Sumatera, Taiwan, Thailand, Vietnam
Plant parts Stem
Other cancers Breast cancer, Liver cancer, Cervical cancer, Colorectal cancer
Target gene or protein NA
Gene or Protein evidence NA
Target pathways NA
IC50 Hexane extract - 12.88±0.45 µg/ml against MCF-7 Ethyl acetate extract - 18.07±1.60 µg/ml against MCF-7 Chloroform extract - 27.06±1.67 µg/ml against MCF-7 Methanol extract - 23.43±1.80 µg/ml against MCF-7
Potency NA
Cell line/ mice model NA
Additional information  NA
PubChem ID NA
Additional PMIDs NA
Additional sources of information NA
Safety NA