| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1224 | |
| Phytochemical name or plant extracts | Clausena excavata root extract | |
| PMID | 23178663 | |
| Literature evidence | Acridine orange/propidium iodide staining was used to detect cells in early apoptosis and high content screening (HCS) to observe nuclear condensation, cell permeability, mitochondrial membrane potential (MMP) and cytochrome c release. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Hexane, Chloroform,ethyl acetate and MeOH extract | |
| Source of phytochemicals or plant Extracts | Clausena excavata Burm | |
| Geographical availability | Assam, Bangladesh, Borneo, Cambodia, China South-Central, China Southeast, East Himalaya, Hainan, India, Jawa, Laos, Lesser Sunda Is., Malaya, Myanmar, Nepal, New Guinea, Philippines, Sulawesi, Sumatera, Taiwan, Thailand, Vietnam | |
| Plant parts | Root | |
| Other cancers | Breast cancer, Liver cancer, Cervical cancer, Colorectal cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | Hexane extract - 18.28±0.45 µg/ml against MCF-7 Ethyl acetate extract - 13.90±1.60 µg/ml against MCF-7 Chloroform extract - 10.28±0.70 µg/ml against MCF-7 Methanol extract - 50.12±6.40 µg/ml against MCF-7 | |
| Potency | NA | |
| Cell line/ mice model | HL-60, HT-29, HepG2, MCF-7, HeLa | |
| Additional information | NA | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | NA | |
| Safety | NA |