Phytochemical Name : Clauselenisin A

Properties Information
PhytoCAT-ID PhytoCAT-1928
Phytochemical name or plant extracts Clauselenisin A
PMID 29667419
Literature evidence Furanocoumarins with potential antiproliferative activities from Clausena lenis.
IUPAC name 9-{[(2E,5E,7S)-7,8-dihydroxy-3,7-dimethylocta-2,5-dien-1-yl]oxy}-7H-furo[3,2-g]chromen-7-one
Phytochemicals’ class or type of plant extracts Furanocoumarin
Source of phytochemicals or plant Extracts Clausena lenis
Geographical availability China South-Central, China Southeast, Hainan, Laos, Thailand, Vietnam
Plant parts Leaves and stem
Other cancers Breast cancer, Colon cancer, Liver cancer, Lung cancer, Leukemia
Target gene or protein NA
Gene or Protein evidence NA
Target pathways NA
IC50 0.45 ± 0.04 μM against MCF-7
Potency The antiproliferative activities against several human cancer cell lines of 1–6 were also investigated, and found to be quite potent.
Cell line/ mice model HL-60, SMMC-7721, A-549, MCF-7 and SW480
Additional information  NA
PubChem ID NA
Additional PMIDs NA
Additional sources of information https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:772149-1
Safety NA