Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-1928 | |
Phytochemical name or plant extracts | Clauselenisin A | |
PMID | 29667419 | |
Literature evidence | Furanocoumarins with potential antiproliferative activities from Clausena lenis. | |
IUPAC name | 9-{[(2E,5E,7S)-7,8-dihydroxy-3,7-dimethylocta-2,5-dien-1-yl]oxy}-7H-furo[3,2-g]chromen-7-one | |
Phytochemicals’ class or type of plant extracts | Furanocoumarin | |
Source of phytochemicals or plant Extracts | Clausena lenis | |
Geographical availability | China South-Central, China Southeast, Hainan, Laos, Thailand, Vietnam | |
Plant parts | Leaves and stem | |
Other cancers | Breast cancer, Colon cancer, Liver cancer, Lung cancer, Leukemia | |
Target gene or protein | NA | |
Gene or Protein evidence | NA | |
Target pathways | NA | |
IC50 | 0.45 ± 0.04 μM against MCF-7 | |
Potency | The antiproliferative activities against several human cancer cell lines of 1–6 were also investigated, and found to be quite potent. | |
Cell line/ mice model | HL-60, SMMC-7721, A-549, MCF-7 and SW480 | |
Additional information | NA | |
PubChem ID | NA | |
Additional PMIDs | NA | |
Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:772149-1 | |
Safety | NA |