| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1220 | |
| Phytochemical name or plant extracts | Clausehainanines D | |
| PMID | 29232633 | |
| Literature evidence | Alkaloids from Clausena hainanensis with their potential antiproliferative activities. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Alkaloid | |
| Source of phytochemicals or plant Extracts | Clausena hainanensis | |
| Geographical availability | Hainan | |
| Plant parts | Leaves and stem. | |
| Other cancers | Breast cancer, Lung cancer, Leukemia | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 0.38 ± 0.07 µM against MCF-7 | |
| Potency | These findings suggest that the discoveries of these Alkaloids with significant cytotoxic activities isolated from C. hainanensis could be of great importance to the development of new anticancer agents. | |
| Cell line/ mice model | HL-60, SMMC-7721, A-549, MCF-7, SW480 | |
| Additional information | Five new Alkaloids, clausehainanines A-E (1-5), together with seven known analogues (6-12) were isolated from the stems and leaves of C. hainanensis. | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:961410-1 | |
| Safety | NA |