Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-137 | |
Phytochemical name or plant extracts | Cirsium rivulare essential oil | |
PMID | 22474978 | |
Literature evidence | These concentrations were below the level able to inhibit the proliferation of healthy cells. | |
IUPAC name | NA | |
Phytochemicals’ class or type of plant extracts | Essential oil | |
Source of phytochemicals or plant Extracts | Cirsium rivulare | |
Geographical availability | Albania, Austria, Baltic States, Belarus, Central European Rus, Czechoslovakia, France, Germany, Great Britain, Hungary, Northwest European R, Poland, Romania, Spain, Switzerland, Ukraine, Yugoslavia | |
Plant parts | Root | |
Other cancers | Breast cancer | |
Target gene or protein | NA | |
Gene or Protein evidence | NA | |
Target pathways | NA | |
IC50 | 110 to 140 μg/mL against MCF-7 and MDA-MB-231 | |
Potency | The essential oils of the roots have moderate anti-proliferative activity, with IC50 values ranging from 110 to 140 microg/mL. These concentrations were below the level able to inhibit the proliferation of healthy cells. | |
Cell line/ mice model | MCF-7, MDA-MBA-231 | |
Additional information | NA | |
PubChem ID | NA | |
Additional PMIDs | NA | |
Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:195931-1 | |
Safety | NA |