| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-421 | |
| Phytochemical name or plant extracts | Cinnamomum cassia extract | |
| PMID | 32807070 | |
| Literature evidence | DNA damage protecting activity of the acetone extract is studied with the comet assay. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Ethyl acetate extract | |
| Source of phytochemicals or plant Extracts | Cinnamomum cassia | |
| Geographical availability | Bangladesh, Borneo, China South-Central, China Southeast, Hainan, Jawa, Lesser Sunda Is., Myanmar, Philippines, Sulawesi, Sumatera, Taiwan, Vietnam | |
| Plant parts | Bark | |
| Other cancers | Breast cancer, Colon cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | Ethyl acetate - 100 μg/ml against MCF-7 | |
| Potency | C. cassia showed promising antioxidant and anticancer activities with significant DNA damage protecting effect. | |
| Cell line/ mice model | MCF-7, MDA-MB-231, HT29 | |
| Additional information | The acetone extract exhibited the highest FRAP value, phenolic and flavonoids contents when compared to the other extracts and could protect 45% mouse fibroblast cell line (3T3-L1) from DNA damage at 30 μg/ml. The lowest IC50 value in DPPH, superoxide, and hydroxyl radicals scavenging was noticed in the ethyl acetate extract. IC50 value obtained for the hexane extract was the lowest compared to the other extracts in scavenging nitric oxide radicals. | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:463328-1 | |
| Safety | NA |