| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-133 | |
| Phytochemical name or plant extracts | Chicory's extract | |
| PMID | 22812448 | |
| Literature evidence | Introducing Cichorium Pumilum as a potential therapeutical agent against drug-induced benign breast tumor in rats. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Extract | |
| Source of phytochemicals or plant Extracts | Cichorium Pumilum | |
| Geographical availability | Afghanistan, Albania, Algeria, Azores, Baleares, Belgium, Bulgaria, Canary Is., Corse, Cyprus, East Aegean Is., Egypt, France, Greece, Gulf States, Iran, Iraq, Italy, Kriti, Lebanon-Syria, Libya, Madeira, Morocco, Palestine, Portugal, Romania, Sardegna, Saudi Arabia, Sicilia, Sinai, Spain, Switzerland, Transcaucasus, Tunisia, Turkey, Turkey-in-Europe, Western Sahara, Xinjiang, Yugoslavia | |
| Plant parts | Aerial parts | |
| Other cancers | Breast cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | These results suggest that chicory extracts could be used as herbal photosensitizing agent in treating benign breast tumor in rats. | |
| Cell line/ mice model | Female Sprague-Dawley rats | |
| Additional information | Chicory's extract has significantly increase P.carbonyl (PC) and malondialdehyde (MDA) and decreases the hepatic levels of total antioxidant capacity (TAC) and superoxide dismutase (SOD) in benign breast tumors-induced group compared to control. It also significantly decrease the number of estrogen receptors ER-positive cells in tumor masses. | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:194540-1 | |
| Safety | NA |