| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-432 | |
| Phytochemical name or plant extracts | Chickpea protease inhibitor concentrate | |
| PMID | 22662866 | |
| Literature evidence | Chickpea (Cicer arietinum) and other plant-derived protease inhibitor concentrates inhibit breast and prostate cancer cell proliferation in vitro. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Protease inhibitor concentrate | |
| Source of phytochemicals or plant Extracts | Cicer arietinum | |
| Geographical availability | Iran, Iraq, Turkey | |
| Plant parts | NA | |
| Other cancers | Breast cancer, Prostate cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | Although soybean PIC did not affect MDA-MB-231 cell proliferation, chickpea PIC exerted a small inhibitory effect on the growth of this metastatic breast cancer cell line at all concentrations tested (25–400 µg/ml). | |
| Cell line/ mice model | MDA-MB-231, PC-3, LNCaP | |
| Additional information | Chickpea PIC significantly inhibited the viability of MDA-MB-231 breast cancer and PC-3 and LNCaP prostate cancer cells at all concentrations tested (25-400 μg/ml). | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:486336-1 | |
| Safety | NA |