| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1077 | |
| Phytochemical name or plant extracts | Chestnoside B | |
| PMID | 28363853 | |
| Literature evidence | These results highlight the occurrence of triterpenoid saponins in sweet chestnut heartwood and their potential for the chemoprevention of breast cancer. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Triterpenoid saponins | |
| Source of phytochemicals or plant Extracts | Castanea sativa | |
| Geographical availability | Albania, East Aegean Is., Greece, Hungary, Iran, Lebanon-Syria, North Caucasus, Transcaucasus, Turkey, Turkey-in-Europe, Yugoslavia | |
| Plant parts | Heartwood | |
| Other cancers | Breast cancer, Prostate cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 12.3 μM against MCF-7 | |
| Potency | These results highlight the occurrence of triterpenoid saponins in sweet chestnut heartwood and their potential for the chemoprevention of breast cancer. | |
| Cell line/ mice model | MCF-7, PC3 | |
| Additional information | NA | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:295349-1 | |
| Safety | NA |