| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1003 | |
| Phytochemical name or plant extracts | Cephalinone D | |
| PMID | 25686035 | |
| Literature evidence | Among the compounds isolated, tryptanthrin (6), phaitanthrin A (7), cephalinone D (19), and flavanthrin (30) showed significant cytotoxicity against MCF-7, NCI-H460, and SF-268 cell lines. | |
| IUPAC name | 2-[3-oxo-2-[3-oxo-2-(3-oxoindol-2-yl)-1H-indol-2-yl]-1H-indol-2-yl]indol-3-one | |
| Phytochemicals’ class or type of plant extracts | NA | |
| Source of phytochemicals or plant Extracts | Cephalantheropsis gracilis | |
| Geographical availability | Assam, Bangladesh, China South-Central, China Southeast, Hainan, Japan, Laos, Maluku, Myanmar, Nansei-shoto, Philippines, Taiwan, Thailand, Vietnam | |
| Plant parts | Aerial parts | |
| Other cancers | Breast cancer, Lung cancer, Glioma | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 7.6 ± 0.7 μM against MCF-7 | |
| Potency | Among the compounds isolated, tryptanthrin (6), phaitanthrin A (7), cephalinone D (19), and flavanthrin (30) showed significant cytotoxicity against MCF-7, NCI-H460, and SF-268 cell lines. | |
| Cell line/ mice model | MCF-7, NCI-H460, and SF-269 | |
| Additional information | NA | |
| PubChem ID | 16091613 | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:622415-1 | |
| Safety | NA |