Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-702 | |
Phytochemical name or plant extracts | Catechin | |
PMID | 26922854 | |
Literature evidence | Quercetin showed significant cytotoxic activity against HepG2 and MCF-7 cell lines with IC50 values of 4.88 and 0.87 μg/mL, respectively. | |
IUPAC name | (2R,3S)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol | |
Phytochemicals’ class or type of plant extracts | Flavonoid | |
Source of phytochemicals or plant Extracts | Calligonum polygonoides | |
Geographical availability | Gulf States, Iran, Iraq, Kuwait, Lebanon-Syria, Pakistan, Palestine, Saudi Arabia, Sinai, Transcaucasus, Turkey, Yemen | |
Plant parts | Aerial parts | |
Other cancers | Breast cancer, Liver cancer | |
Target gene or protein | NA | |
Gene or Protein evidence | NA | |
Target pathways | NA | |
IC50 | 27.78 µg/ml against MCF-7 | |
Potency | Catechin and its gallate are major ingredients in green tea and their anti-oxidant and cancer preventive effects have been widely investigated. | |
Cell line/ mice model | MCF-7, HepG2 | |
Additional information | Defined Green Tea Catechin Extract in Treating Women With Hormone Receptor Negative Stage I-III Breast Cancer | |
PubChem ID | 9064 | |
Additional PMIDs | 11060796 | |
Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:693386-1 NCT00516243 | |
Safety | NA |