| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1045 | |
| Phytochemical name or plant extracts | Camphoratin F | |
| PMID | 21115251 | |
| Literature evidence | Compounds 21, 25, 26, 29-31, 33, and 36 demonstrated potent anti-inflammatory activity by inhibiting lipopolysaccharide (LPS)-induced nitric oxide (NO) production with IC(50) values of 2.5, 1.6, 3.6, 0.6, 4.1, 4.2, 2.5, and 1.5μM, respectively, which were better than those of the nonspecific nitric oxide synthase (NOS) inhibitor N-nitro-l-arginine methyl ester (l-NAME) (IC(50): 25.8μM). | |
| IUPAC name | methyl (6S)-6-[(1R,3aR,4S,5aS,6S,9aS,11aR)-4-hydroxy-6,9a,11a-trimethyl-7,10-dioxo-1H,2H,3H,3aH,4H,5H,5aH,6H,7H,8H,9H,9aH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-methyl-3-methylideneheptanoate | |
| Phytochemicals’ class or type of plant extracts | Triterpenoid | |
| Source of phytochemicals or plant Extracts | Taiwanofungus camphoratus | |
| Geographical availability | Taiwan | |
| Plant parts | Fruiting body | |
| Other cancers | Breast cancer, Liver cancer, Cervical cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | ED50 - 7.9 µg/mL against MCF-7 | |
| Cell line/ mice model | MCF-7, Hep2, Hela | |
| Additional information | NA | |
| PubChem ID | 50900841 | |
| Additional PMIDs | 30123668 | |
| Additional sources of information | https://fungidb.org/fungidb/app/record/compound/CHEBI:70305 | |
| Safety | NA |