Phytochemical Name : Calcitrinone A

Properties Information
PhytoCAT-ID PhytoCAT-1071
Phytochemical name or plant extracts Calcitrinone A
PMID 35227860
Literature evidence Calcitrinone A decreased the total intracellular ATP levels, inhibited proliferation, and induced apoptosis in MDA-MB-231 cells, but was less toxic to peripheral blood mononuclear cells.
IUPAC name NA
Phytochemicals’ class or type of plant extracts Phloroglucinol dimer
Source of phytochemicals or plant Extracts Callistemon citrinus
Geographical availability New South Wales, Queensland, Victoria
Plant parts Leaves
Other cancers Breast cancer
Target gene or protein NA
Gene or Protein evidence NA
Target pathways NA
IC50 NA
Potency NA
Cell line/ mice model MDA-MB-231
Additional information  Calcitrinone A might be a promising anticancer lead compound acting through the interference with the mitochondrial complex II activity.
PubChem ID NA
Additional PMIDs NA
Additional sources of information https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:591369-1
Safety NA