| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-194 | |
| Phytochemical name or plant extracts | Bryonia multiflora extract | |
| PMID | 34024207 | |
| Literature evidence | The current study has shown that BMST induces autophagy in MCF-7 and MDA-MB-231 cells via regulating the lncRNAs revealing that BMST could be a promising therapeutic agent. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Extract | |
| Source of phytochemicals or plant Extracts | Bryonia multiflora | |
| Geographical availability | Iran, Iraq, Lebanon-Syria, Turkey | |
| Plant parts | NA | |
| Other cancers | Breast cancer | |
| Target gene or protein | Bcl-2, p21 | |
| Gene or Protein evidence | BMST treated MCF-7 and MDA-MB-231 cells had increased levels of autophagy markers whereas decreased levels of Bcl-2. p21 levels were also found to be increased in both cells. | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | The current study has shown that BMST induces autophagy in MCF-7 and MDA-MB-231 cells via regulating the lncRNAs revealing that BMST could be a promising therapeutic agent. | |
| Cell line/ mice model | MCF-7, MDA-MB-231 | |
| Additional information | Analysis of lncRNA expressions has shown that BMST treatment led to changes in the expression levels of several lncRNAs playing roles in autophagy. | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:291651-1 | |
| Safety | NA |