Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-1770 | |
Phytochemical name or plant extracts | Brevione A | |
PMID | 22412815 | |
Literature evidence | Compounds 2 and 5 showed significant cytotoxicity against MCF-7 cells, which is comparable to the positive control cisplatin. | |
IUPAC name | (2S,4'aR,4'bR,8'aR,10'aR)-2',4'b,6,7,8',8',10'a-heptamethyl-3,4,4'a,4'b,7',8',8'a,9',10',10'a-decahydro-4'H-spiro[furo[3,2-c]pyran-2,1'-phenanthrene]-4,7'-dione | |
Phytochemicals’ class or type of plant extracts | Diterpenoid | |
Source of phytochemicals or plant Extracts | Penicillium sp | |
Geographical availability | Deep sea sediment | |
Plant parts | NA | |
Other cancers | Breast cancer | |
Target gene or protein | NA | |
Gene or Protein evidence | NA | |
Target pathways | NA | |
IC50 | 28.4 µM against MCF-7 | |
Potency | NA | |
Cell line/ mice model | MCF-7 | |
Additional information | NA | |
PubChem ID | 10669938 | |
Additional PMIDs | NA | |
Additional sources of information | NA | |
Safety | NA |