| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1830 | |
| Phytochemical name or plant extracts | Boswellia ovalifoliolata extract (BL EthOH) | |
| PMID | 24908637 | |
| Literature evidence | Apoptotic studies showed that BL EthOH was able to induce apoptosis and western blot studies demonstrated that BL EthOH significantly decreased the Phospho-NF-κB (ser536), PCNA, anti-apoptotic protein Bcl-2 expression and increased the expression of pro-apoptotic protein Bax, in MDA-MB-231 and MDA-MB-453 cell lines when compared with untreated cells. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Ethanolic extract | |
| Source of phytochemicals or plant Extracts | Boswellia ovalifoliolata | |
| Geographical availability | India | |
| Plant parts | Leaves | |
| Other cancers | Breast cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 67.48 ± 5.45 μg/ml against MDA-MB-231, 70.03 ± 4.76 μg/ml against MDA-MB-453 | |
| Potency | Besides, BL EthOH has synergistic chemosensitizing effects on TNBC cells and increased the cytotoxicity of doxorubicin and cisplatin. | |
| Cell line/ mice model | MDA-MB-231 and MDA-MB-453 | |
| Additional information | NA | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:127059-1 | |
| Safety | NA |