Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-152 | |
Phytochemical name or plant extracts | Black raspberry | |
PMID | 17147415 | |
Literature evidence | The berry extracts were evaluated for their ability to inhibit the growth of human oral (KB, CAL-27), breast (MCF-7), colon (HT-29, HCT116), and prostate (LNCaP) tumor cell lines at concentrations ranging from 25 to 200 micro g/mL. | |
IUPAC name | NA | |
Phytochemicals’ class or type of plant extracts | Phenolic constituents | |
Source of phytochemicals or plant Extracts | Rubus occidentalis | |
Geographical availability | Alabama, Arkansas, Connecticut, Delaware, District of Columbia, Georgia, Illinois, Indiana, Iowa, Kansas, Kentucky, Maine, Maryland, Massachusetts, Michigan, Minnesota, Mississippi, Missouri, Nebraska, New Brunswick, New Hampshire, New Jersey, New York, North Carolina, North Dakota, Ohio, Oklahoma, Ontario, Pennsylvania, Québec, Rhode I., South Carolina, South Dakota, Tennessee, Vermont, Virginia, West Virginia, Wisconsin | |
Plant parts | Fruits | |
Other cancers | Breast cancer, Oral cancer, Prostate cancer, Colon cancer | |
Target gene or protein | NA | |
Gene or Protein evidence | NA | |
Target pathways | NA | |
IC50 | 145.40 (IC50 values were calculated by nonlinear regression) | |
Potency | NA | |
Cell line/ mice model | KB, CAL-27, MCF-7, HT-29, HCT116, LNCaP | |
Additional information | The berry extracts were also evaluated for their ability to stimulate apoptosis of the COX-2 expressing colon cancer cell line, HT-29. | |
PubChem ID | NA | |
Additional PMIDs | 20043264 17147415 | |
Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:223350-2 | |
Safety | NA |