| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-837 | |
| Phytochemical name or plant extracts | Bisabolocurcumin ether | |
| PMID | 23153397 | |
| Literature evidence | Terpecurcumins A-I from the rhizomes of Curcuma longa: absolute configuration and cytotoxic activity. | |
| IUPAC name | (6S)-6-[(1R,2R,5S)-5-hydroxy-2-[4-[(1E,3Z,6E)-3-hydroxy-7-(4-hydroxy-3-methoxyphenyl)-5-oxohepta-1,3,6-trienyl]-2-methoxyphenoxy]-4-methylcyclohex-3-en-1-yl]-2-methylhept-2-en-4-one | |
| Phytochemicals’ class or type of plant extracts | Curcuminoid | |
| Source of phytochemicals or plant Extracts | Curcuma longa | |
| Geographical availability | India | |
| Plant parts | Rhizome | |
| Other cancers | Breast cancer, Lung cancer, Liver cancer | |
| Target gene or protein | p38, p53 | |
| Gene or Protein evidence | ROS induction by T1 resulted in activation of p38/H2AX axis and p53. | |
| Target pathways | NA | |
| IC50 | 10.6 μM against MDA-MB-231 | |
| Potency | Our findings provide mechanistic support for the potential use of terpene-conjugated curcuminoids as a novel class of cancer chemopreventive agents. | |
| Cell line/ mice model | MDA-MB-231, A549, HepG2 | |
| Additional information | NA | |
| PubChem ID | 71463189 | |
| Additional PMIDs | 25647442 | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:796451-1 | |
| Safety | NA |