| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1921 | |
| Phytochemical name or plant extracts | Baker's yeast | |
| PMID | 29161917 | |
| Literature evidence | Baker's yeast may represent a novel adjuvant for chemotherapy treatment. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Natural product | |
| Source of phytochemicals or plant Extracts | Saccharomyces cerevisiae | |
| Geographical availability | NA | |
| Plant parts | NA | |
| Other cancers | Breast, Colon cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | IC50 (2 × 10−6 M/L) for 4T1 cell and IC50 = 4 × 10−5 M/L for 109 cells/mL yeast for MCF-7 cell line. | |
| Potency | These data suggest that dietary baker's yeast is an effective chemosensitizer and can enhance the apoptotic capacity of paclitaxel against breast cancer cells in vitro. | |
| Cell line/ mice model | The metastatic murine 4T1 line, the murine Ehrlich ascites carcinoma (EAC) line, and the human breast cancer MCF-7 cell line. | |
| Additional information | Baker's yeast in the presence of paclitaxel increased the sensitivity of 4T1 cells to chemotherapy and caused effects that were greater than either treatment alone. | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | NA | |
| Safety | NA |