Phytochemical Name : Bacopa monnieri extract

Properties Information
PhytoCAT-ID PhytoCAT-1065
Phytochemical name or plant extracts Bacopa monnieri extract
PMID 26681894
Literature evidence CONCLUSION: The results showed good cytotoxic activity in DCM fraction in both the cell lines may be due to the presence of cucurbitacins and betulinic acid in DCM fraction.
IUPAC name NA
Phytochemicals’ class or type of plant extracts Ethanolic Extract
Source of phytochemicals or plant Extracts Bacopa monnieri
Geographical availability Afghanistan, Alabama, Aldabra, Argentina Northeast, Argentina Northwest, Argentina South, Arizona, Assam, Bahamas, Bangladesh, Belize, Bermuda, Bolivia, Brazil Northeast, Brazil South, Brazil Southeast, Cambodia, Cayman Is., Chagos Archipelago, Chile Central, Chile North, China South-Central, China Southeast, Colombia, Congo, Costa Rica, Cuba, Dominican Republic, East Himalaya, Ecuador, Egypt, El Salvador, Equatorial Guinea, Florida, French Guiana, Gabon, Georgia, Gilbert Is., Guatemala, Gulf States, Hainan, Haiti, Hawaii, Honduras, India, Iran, Jamaica, KwaZulu-Natal, Laccadive Is., Laos, Leeward Is., Louisiana, Malaya, Maldives, Marianas, Maryland, Mauritius, Mexico Central, Mexico Gulf, Mexico Northeast, Mexico Northwest, Mexico Southeast, Mexico Southwest, Mississippi, Mozambique, Myanmar, Nepal, Nicaragua, Nigeria, North Carolina, Oklahoma, Oman, Pakistan, Palestine, Panamá, Paraguay, Peru, Puerto Rico, Rodrigues, Réunion, Saudi Arabia, Sinai, Socotra, Somalia, South Carolina, South China Sea, Sri Lanka, Taiwan, Texas, Thailand, Trinidad-Tobago, Uruguay, Venezuela, Vietnam, Virginia, West Himalaya, Windward Is., Yemen
Plant parts NA
Other cancers Breast cancer
Target gene or protein NA
Gene or Protein evidence NA
Target pathways NA
IC50 72.0 μg/mL against MCF-7 75.0 μg/mL against MDA-MB 231
Potency NA
Cell line/ mice model MCF-7, MDA-MB 231
Additional information  These findings suggest that Bacopa monnieri is a potential cognitive enhancer and neuroprotectant against Alzheimer's disease.
PubChem ID NA
Additional PMIDs 19808086
Additional sources of information https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:1072674-2
Safety NA