| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-593 | |
| Phytochemical name or plant extracts | Azadirone | |
| PMID | 26320684 | |
| Literature evidence | The antiplasmodial activities of the crude extracts and the isolated constituents against the D6 and W2 strains of Plasmodium falciparum were determined using the semiautomated micro dilution technique that measures the ability of the extracts to inhibit the incorporation of (G-(3)H, where G is guanine) hypoxanthine into the malaria parasite. | |
| IUPAC name | [(5R,7R,8R,9R,10R,13S,17R)-17-(furan-3-yl)-4,4,8,10,13-pentamethyl-3-oxo-5,6,7,9,11,12,16,17-octahydrocyclopenta[a]phenanthren-7-yl] acetate | |
| Phytochemicals’ class or type of plant extracts | Triterpenoid | |
| Source of phytochemicals or plant Extracts | Turraea nilotica Turraea robusta | |
| Geographical availability | Turraea nilotica - Burundi, Ethiopia, Kenya, Malawi, Mozambique, Northern Provinces, Somalia, Sudan, Swaziland, Tanzania, Zambia, Zimbabwe Turraea robusta - Cameroon, Kenya, Malawi, Tanzania, Uganda, Zambia, Zaïre | |
| Plant parts | Root Stem | |
| Other cancers | Breast cancer, Larynx cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 14.4±0.0 µg/mL against 4T1 | |
| Potency | NA | |
| Cell line/ mice model | 4T1, HEp2, Vero | |
| Additional information | NA | |
| PubChem ID | 10906239 | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:579805-1 https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:579836-1 | |
| Safety | NA |