| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-340 | |
| Phytochemical name or plant extracts | Avenanthramide-C | |
| PMID | 29075150 | |
| Literature evidence | BACKGROUND: Avenanthramides (AVN) are a relatively unstudied family of phytochemicals that could be novel chemotherapeutics. | |
| IUPAC name | 2-[[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]amino]-5-hydroxybenzoic acid | |
| Phytochemicals’ class or type of plant extracts | Alkaloid | |
| Source of phytochemicals or plant Extracts | Avena sativa | |
| Geographical availability | Iran, Iraq | |
| Plant parts | NA | |
| Other cancers | Breast cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | Breast cancer cells treated with AVN-C have a decrease in cell viability, an increase in the sub G1 population, and stain positive for both annexin V and caspase activity, indicating that AVN-C induces apoptosis in breast cancer cells. | |
| Cell line/ mice model | MDA-MB-231 | |
| Additional information | These compounds may be able to act as chemotherapeutics as demonstrated through future in vivo studies. | |
| PubChem ID | 11723200 | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:391732-1 | |
| Safety | NA |