| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-803 | |
| Phytochemical name or plant extracts | Aucklandia Lappa Decne extract | |
| PMID | 30051673 | |
| Literature evidence | We report for the first time that lyophilized ALD selectively influences apoptosis through alternative apoptotic pathways in both breast and cervical human cancer cells. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Ethanolic Extract | |
| Source of phytochemicals or plant Extracts | Aucklandia lappa | |
| Geographical availability | China North-Central, China South-Central, China Southeast, East Himalaya, Hainan, Inner Mongolia, Manchuria, Nepal, Pakistan, Qinghai, Tibet, Vietnam, West Himalaya, Xinjiang | |
| Plant parts | Root | |
| Other cancers | Breast cancer, Cervical cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | The viability of T-47D, HeLa, and HEp-2 cells were declined in a measurements subordinate way and demonstrated cytotoxic activity with the IC50 concentration of the extract observed to be between 50μg/mL to 75μg/mL. | |
| Potency | Interestingly, lyophilized ALD significantly (p<0.005) repressed the growth of HEp-2 and T-47D cells after treatment for 48hrs while 24hrs treatment significantly suppressed T-47D and HeLa cells | |
| Cell line/ mice model | T47D, HeLa, HEp-2 | |
| Additional information | We report for the first time that lyophilized ALD selectively influences apoptosis through alternative apoptotic pathways in both breast and cervical human cancer cells. | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:77180917-1 | |
| Safety | NA |