| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1970 | |
| Phytochemical name or plant extracts | Atranorin | |
| PMID | 20837130 | |
| Literature evidence | One of the ways for searching for potentially new anti-cancer drugs is the testing of various naturally synthesized compounds. | |
| IUPAC name | (3-hydroxy-4-methoxycarbonyl-2,5-dimethylphenyl) 3-formyl-2,4-dihydroxy-6-methylbenzoate | |
| Phytochemicals’ class or type of plant extracts | Depside | |
| Source of phytochemicals or plant Extracts | Stereocaulon alpinum | |
| Geographical availability | NA | |
| Plant parts | Lichen | |
| Other cancers | Breast cancer, Cervical cancer, Liver cancer, Ovarian cancer, Leukemia | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | >200 μM against MCF-7 and SK-BR-3 | |
| Potency | Our study reports on the sensitivity of up to nine human cancer cell lines (A2780, HeLa, MCF-7, SK-BR-3, HT-29, HCT-116 p53(+/+), HCT-116 p53(-/-), HL-60 and Jurkat) to the anti-proliferative/cytotoxic effects of four typical secondary metabolites of lichens (parietin, atranorin, usnic acid and gyrophoric acid). | |
| Cell line/ mice model | A2780, HeLa, MCF-7, SKBR-3, HT-29, HCT-116 p53(+/+), HCT-116 p53(-/-), HL-60 and Jurkat | |
| Additional information | NA | |
| PubChem ID | 68066 | |
| Additional PMIDs | 15784343 | |
| Additional sources of information | NA | |
| Safety | NA |