Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-897 | |
Phytochemical name or plant extracts | Asafoetida | |
PMID | 28690055 | |
Literature evidence | CONCLUSIONS: The present study demonstrated that asafoetida has potent antitumor and antimetastasis effects on breast cancer and is a potential source of natural antitumor products. | |
IUPAC name | NA | |
Phytochemicals’ class or type of plant extracts | Gum | |
Source of phytochemicals or plant Extracts | Ferula assa-foetida | |
Geographical availability | Iran | |
Plant parts | Raisin | |
Other cancers | Breast cancer | |
Target gene or protein | NA | |
Gene or Protein evidence | NA | |
Target pathways | NA | |
IC50 | The IC50 asafoetida highest inhibitory effect was obtained at 32 μg/ml in this work, our results also showed that the IC50 of antioxidant activity of asafoetida was 109 μg/ml | |
Potency | The present study demonstrated that asafoetida has potent antitumor and antimetastasis effects on breast cancer and is a potential source of natural antitumor products. | |
Cell line/ mice model | 4T1 | |
Additional information | Apart from the antitumor effect, asafoetida decreased lung, liver and kidney metastasis and also increased areas of necrosis in the tumor tissue respectively. | |
PubChem ID | NA | |
Additional PMIDs | 28900317 32606682 31516858 28690055 | |
Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:842190-1 | |
Safety | NA |