| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-114 | |
| Phytochemical name or plant extracts | Artemisia diffusa extract | |
| PMID | 21592012 | |
| Literature evidence | Artemisia could be also considered as a promising chemotherapeutic agent in cancer treatment. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Methanolic extract, Ethyl acetate extract, Dichloromethane extract, n-Hexane extract | |
| Source of phytochemicals or plant Extracts | Artemisia diffusa | |
| Geographical availability | Afghanistan, Iran, Kazakhstan, Uzbekistan | |
| Plant parts | Aerial parts | |
| Other cancers | Breast cancer, Stomach cancer, Cervical cancer, Colon cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | Methanol extract - 115 µg/ml against MCF-7 Ethyl acetate extract - 103 µg/ml against MCF-7 Dichloromethane extract - 88 µg/ml against MCF-7 n-Hexane extract - >2000 µg/ml against MCF-7 | |
| Potency | Although MCF-7 cells were best inhibited by A. ciniformis dichloromethane (IC50 value: 29 µg/ml) and A. vulgaris ethyl acetate (IC50 value: 57 µg/ml) extracts, it was not inhibited by n-hexane extract of A. diffusa (IC50 value: more than 2000 µg/ml). | |
| Cell line/ mice model | AGS, HeLa, HT-29, MCF-7 | |
| Additional information | NA | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:179413-1 | |
| Safety | NA |