| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1326 | |
| Phytochemical name or plant extracts | Ardicrenin | |
| PMID | 33516453 | |
| Literature evidence | Ardicrenin (6) showed significant cytotoxicity, with IC50 values of 1.17 ± 0.01, 1.19 ± 0.06, 3.52 ± 0.23, and 16.61 ± 1.02 μmol·L-1, respectively. | |
| IUPAC name | (4S,5R,10S,13R,14R,20S,22S)-22-hydroxy-4,5,9,9,13,20-hexamethyl-10-[(2S,3R,4S,5S)-4-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-5-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-24-oxahexacyclo[15.5.2.01,18.04,17.05,14.08,13]tetracosane-20-carbaldehyde | |
| Phytochemicals’ class or type of plant extracts | Ethanolic extract | |
| Source of phytochemicals or plant Extracts | Ardisia crenata | |
| Geographical availability | Assam, Cambodia, China South-Central, China Southeast, Hainan, India, Japan, Korea, Laos, Malaya, Myanmar, Nansei-shoto, Philippines, Sri Lanka, Taiwan, Thailand, Tibet, Vietnam | |
| Plant parts | Root | |
| Other cancers | Breast cancer, Lung cancer, Liver cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 1.19 ± 0.06 µmol/L against MCF-7 16.61 ± 1.02 µmol/L against MDA-MB-231 | |
| Potency | NA | |
| Cell line/ mice model | A549, MCF-7, HepG2 and MDA-MB-231 | |
| Additional information | NA | |
| PubChem ID | 3083371 | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:586890-1 | |
| Safety | NA |