| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1861 | |
| Phytochemical name or plant extracts | Apodytes dimidiata extract | |
| PMID | 26218335 | |
| Literature evidence | In the present study, significant cytotoxicity was exhibited by the methanolic extract of the A. dimidiata leaf against various cancer cell lines. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Methanolic extract | |
| Source of phytochemicals or plant Extracts | Apodytes dimidiata | |
| Geographical availability | Aldabra, Angola, Assam, Borneo, Burundi, Cambodia, Cameroon, Cape Provinces, China South-Central, China Southeast, Comoros, Eritrea, Ethiopia, Hainan, India, Jawa, Kenya, KwaZulu-Natal, Lesser Sunda Is., Madagascar, Malawi, Malaya, Maluku, Mauritius, Mozambique, Myanmar, Nigeria, Northern Provinces, Philippines, Rwanda, Réunion, Sri Lanka, Sudan, Sulawesi, Sumatera, Swaziland, Tanzania, Thailand, Uganda, Vietnam, Zambia, Zaïre, Zimbabwe | |
| Plant parts | Leaves | |
| Other cancers | Breast cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | Methanolic fraction - 0.92 to 3.95 µg/mL against Jurkat, Ehrlich's ascites carcinoma, SK-BR-3 | |
| Potency | NA | |
| Cell line/ mice model | Jurkat, Ehrlich's ascites carcinoma, SKBR-3 | |
| Additional information | Reduces solid tumour volume in mice to 55.14% (IN VIVO - Ehrlich's ascites tumour-bearing mice) | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:434212-1 | |
| Safety | NA |