| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1430 | |
| Phytochemical name or plant extracts | Antirhine | |
| PMID | 29072098 | |
| Literature evidence | Alkaloids 1-4 exhibited significant inhibitory effects against various human cancer cell lines with IC50 values comparable to those of cisplatin. | |
| IUPAC name | (2R)-2-[(2S,12bS)-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl]but-3-en-1-ol | |
| Phytochemicals’ class or type of plant extracts | Alkaloid | |
| Source of phytochemicals or plant Extracts | Nauclea orientalis | |
| Geographical availability | Angola, Assam, Bangladesh, Benin, Bismarck Archipelago, Borneo, Burkina, Cabinda, Cambodia, Cameroon, Central African Republic, Chad, China Southeast, Congo, Equatorial Guinea, Ethiopia, Gabon, Gambia, Ghana, Guinea, Guinea-Bissau, Gulf of Guinea Is., Hainan, Ivory Coast, Jawa, Kenya, Laos, Lesser Sunda Is., Liberia, Malawi, Malaya, Mali, Maluku, Mauritania, Mozambique, Myanmar, New Guinea, Nigeria, Northern Territory, Philippines, Queensland, Senegal, Sierra Leone, Solomon Is., Sri Lanka, Sudan, Sulawesi, Sumatera, Tanzania, Thailand, Togo, Uganda, Vietnam, Zambia, Zaïre | |
| Plant parts | Leaves and stem | |
| Other cancers | Breast cancer, Leukemia, Liver cancer, Lung cancer, Colorectal cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 10.38 ± 0.21 µM against MCF-7 | |
| Potency | NA | |
| Cell line/ mice model | HL-60, SMMC-7721, A-549, MCF-7, SW480 | |
| Additional information | NA | |
| PubChem ID | 5462421 | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:327870-2 | |
| Safety | NA |