| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-583 | |
| Phytochemical name or plant extracts | Amoora rohituka extract | |
| PMID | 21584193 | |
| Literature evidence | For MCF-7 cancer cells, the chittagonga (Pet-Ether and CH(2)Cl(2)) and rohituka (Pet-Ether) extracts induced cytotoxicity, the chittagonga (EtoAC) and rohituka (MeOH) extracts did not induce cytotoxicity. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Petroleum ether, Dichloromethane extract, Ethanolic extract | |
| Source of phytochemicals or plant Extracts | Amoora rohituka | |
| Geographical availability | Andaman Is., Assam, Bangladesh, Bismarck Archipelago, Borneo, Cambodia, China South-Central, China Southeast, East Himalaya, Hainan, India, Jawa, Laos, Lesser Sunda Is., Malaya, Maluku, Myanmar, New Guinea, Nicobar Is., Philippines, Solomon Is., Sri Lanka, Sulawesi, Sumatera, Taiwan, Thailand, Vietnam | |
| Plant parts | Stem | |
| Other cancers | Breast cancer, Pancreatic Cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | Pet-Ether - ~41 μg/mL against MCF-7 | |
| Potency | For MCF-7 cancer cells, the chittagonga (Pet-Ether and CH(2)Cl(2)) and rohituka (Pet-Ether) extracts induced cytotoxicity; the chittagonga (EtoAC) and rohituka (MeOH) extracts did not induce cytotoxicity. | |
| Cell line/ mice model | MCF-7, HTB-126, Panc-1, Mia-Paca2, and Capan1 | |
| Additional information | Based on these results, further examination of the potential anticancer properties Amoora species and the identification of the active ingredients of these extracts is warranted. | |
| PubChem ID | NA | |
| Additional PMIDs | 23475563 27275107 21898150 19686817 21584193 30846274 17028990 11933149 | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:577535-1 | |
| Safety | The extracts were not cytotoxic to normal fibroblast Hs68 cells, which may be correlated to the specificity of Amoora extracts in targeting cancerous cells. |