| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-935 | |
| Phytochemical name or plant extracts | Alpinia pahangensis extract | |
| PMID | 24083445 | |
| Literature evidence | CONCLUSIONS: The current study suggests that the methanol extract and ethyl acetate fraction of A. pahangensis is a potential source of natural antioxidant for protective as well as prevention of life-threatening diseases. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Methanolic extract, Hexane extract, Ethyl acetate extract, Aqueous extract | |
| Source of phytochemicals or plant Extracts | Alpinia pahangensis | |
| Geographical availability | Malaya | |
| Plant parts | Rhizome | |
| Other cancers | Breast cancer, Lung cancer, Cervical cancer, Colon cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | Methanolic extract - >100μg/ml against MCF-7 Hexane extract - 22.0 ± 1.3μg/ml against MCF-7 Ethyl acetate extract - 50.3 ± 0.3μg/ml against MCF-7 Water extract - >100μg/ml against MCF-7 | |
| Potency | The hexane fraction showed the highest cytotoxic activity with IC50 less than 20 μg/ml against KB, A549, Ca Ski, HCT 116 and HT-29 with the exception of MCF7. | |
| Cell line/ mice model | MCF-7, A549, KB, Ca Ski and HCT 116 | |
| Additional information | The current study suggests that the methanol extract and ethyl acetate fraction of A. pahangensis is a potential source of natural antioxidant for protective as well as prevention of life-threatening diseases. The hexane fraction of A. pahangensis may have the potential to be developed into therapeutic option for treating cancer. | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:872017-1 | |
| Safety | NA |