Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-943 | |
Phytochemical name or plant extracts | Allium sivasicum (AS) extract | |
PMID | 23065225 | |
Literature evidence | These results indicate that A. sivasicum has antitumoral potential against breast cancer. | |
IUPAC name | NA | |
Phytochemicals’ class or type of plant extracts | Extract | |
Source of phytochemicals or plant Extracts | Allium sivasicum | |
Geographical availability | Turkey | |
Plant parts | NA | |
Other cancers | Breast cancer | |
Target gene or protein | NA | |
Gene or Protein evidence | NA | |
Target pathways | These results may suggest that AS induced the apoptosis in breast cancer cells via the caspase cascade pathway. | |
IC50 | 21 ± 1.4 μg/mL against MCF-7 22 ± 1.4 μg/mL against MDA-MB-468 24 ± 1.3 μg/mL against MDA-MB-231 | |
Potency | These results indicate that A. sivasicum has antitumoral potential against breast cancer. | |
Cell line/ mice model | MDA-MB-231, MDA-MB-468, MCF-7 | |
Additional information | NA | |
PubChem ID | NA | |
Additional PMIDs | NA | |
Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:901416-1 | |
Safety | NA |