| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-744 | |
| Phytochemical name or plant extracts | Agrimonia pilosa extract | |
| PMID | 23259680 | |
| Literature evidence | Estrogen-like activity of aqueous extract from Agrimonia pilosa Ledeb. in MCF-7 cells. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Aqueous extract | |
| Source of phytochemicals or plant Extracts | Agrimonia pilosa | |
| Geographical availability | Altay, Assam, Baltic States, Belarus, Central European Rus, China North-Central, China South-Central, China Southeast, East European Russia, East Himalaya, Finland, Hainan, India, Inner Mongolia, Irkutsk, Japan, Jawa, Kazakhstan, Korea, Krasnoyarsk, Laos, Manchuria, Mongolia, Myanmar, Nansei-shoto, Nepal, North Caucasus, North European Russi, Northwest European R, Pakistan, Poland, Primorye, Romania, South European Russi, Taiwan, Thailand, Tibet, Transcaucasus, Tuva, Ukraine, Vietnam, West Himalaya, West Siberia, Xinjiang, Yugoslavia | |
| Plant parts | Aerial parts | |
| Other cancers | Breast cancer | |
| Target gene or protein | pS2, PR | |
| Gene or Protein evidence | Moreover, A. pilosa treatment increased the mRNA expression of the estrogen-responsive genes pS2 and PR (p < 0.05). | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | These results suggest A. pilosa can be used to improve estrogen deficiency-related menopausal symptoms or to treat diseases in postmenopausal women. | |
| Cell line/ mice model | MCF-7 | |
| Additional information | Agrimonia pilosa Ledeb. has shown remarkable effectiveness in the treatment of various diseases, especially enteritis, gastric ulcers, and gastrointestinal bleeding. | |
| PubChem ID | NA | |
| Additional PMIDs | 36046524 | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:720300-1 | |
| Safety | NA |