| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1054 | |
| Phytochemical name or plant extracts | Ageratum conyzoides extract | |
| PMID | 33066411 | |
| Literature evidence | Using MTT assay, the crude extract of Ageratum exhibited IC50 22 and 229 µg/mL against 4T1 and T47D cell proliferations, respectively with a high safety index concluding its potential anti-breast cancer from herbal. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Extract | |
| Source of phytochemicals or plant Extracts | Ageratum conyzoides | |
| Geographical availability | Mexico Central, Mexico Gulf, Mexico Northeast, Mexico Northwest, Mexico Southwest | |
| Plant parts | Aerial parts | |
| Other cancers | Breast cancer | |
| Target gene or protein | MMP9 | |
| Gene or Protein evidence | This corresponds to the results of the in vitro study against MMP9, especially for Ageratum conyzoides where the extract, partitions, and fraction demonstrate quite good activities in inhibiting MMP9. | |
| Target pathways | NA | |
| IC50 | 229 µg/mL against T47D 22 µg/mLagainst 4T1 | |
| Potency | The result indicated that Ageratum was cytotoxic to 4T1 breast cancer cells and has the potential as an anti-proliferative agent. | |
| Cell line/ mice model | T47D, 4T1 | |
| Additional information | NA | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:7086-2 | |
| Safety | NA |