| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-2086 | |
| Phytochemical name or plant extracts | Agave americana extract | |
| PMID | 22247852 | |
| Literature evidence | Research is focusing on the search for new types of natural chemotherapeutic agent that is plant based medicines which are proving to be excellent sources of new compounds. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Methanolic extract | |
| Source of phytochemicals or plant Extracts | Agave americana | |
| Geographical availability | Arizona, Mexico Central, Mexico Gulf, Mexico Northeast, Mexico Northwest, Mexico Southwest, Texas | |
| Plant parts | Leaves | |
| Other cancers | Breast cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 545.9 μg/ml against MCF-7 | |
| Potency | From cytotoxicity study data by SRB and MTT assay, it revealed that methanol extract of Agave americana and aqueous extract of Areca catechu are potent cytotoxic. | |
| Cell line/ mice model | MCF-7, Vero | |
| Additional information | NA | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:319063-2 | |
| Safety | Against Vero cell line, IC50 of methanol extract of Agave americana was found to be 1854 μg/ml whereas aqueous extract of Areca catechu and methanol extract of Strychnos nux-vomica were not showed any significant cytotoxicity activity. |