| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1932 | |
| Phytochemical name or plant extracts | Aegyptinone A | |
| PMID | 29772301 | |
| Literature evidence | The cytotoxic activities of the crude extracts and isolated compounds were evaluated against MCF-7, B16F10, PC-3 and C26 human cancer cell lines, in which compounds 2 and 3 showed significant cytotoxic activities (IC50 2.1-10.3 μM). | |
| IUPAC name | 3,10,10-trimethyl-2H,3H,4H,5H,7H,8H,9H,10H-anthra[1,2-b]furan-4,5-dione | |
| Phytochemicals’ class or type of plant extracts | Diterpenoid | |
| Source of phytochemicals or plant Extracts | Salvia tebesana Bunge | |
| Geographical availability | Iran | |
| Plant parts | Root | |
| Other cancers | Breast cancer , Skin cancer, Prostate cancer, Colon cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 8.19 ± 0.56 μM against MCF-7 | |
| Potency | NA | |
| Cell line/ mice model | MCF-7, B16F10, PC-3, C27 | |
| Additional information | Shows significant cytotoxic activities against MCF-7, B16F10, PC-3 and C26 human cancer cell lines | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | NA | |
| Safety | NA |