| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-528 | |
| Phytochemical name or plant extracts | Adzuki bean extract | |
| PMID | 17048572 | |
| Literature evidence | Author information: (1)First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China. xgzhang666@yahoo.com.cn OBJECTIVE: To explore the estrogenic activity of ethanol extract from adzuki bean Phaseolus angularis and its effect on progesterone receptor (PR) level of human breast cancer MCF-7 cells. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Ethanolic extract | |
| Source of phytochemicals or plant Extracts | Phaseolus angularis | |
| Geographical availability | Assam, China South-Central, China Southeast, East Himalaya, Japan, Myanmar, Nepal, Taiwan, Vietnam | |
| Plant parts | Seeds | |
| Other cancers | Breast cancer | |
| Target gene or protein | PR mRNA and protein | |
| Gene or Protein evidence | The results of RT-PCR and western blotting showed that PR mRNA and protein could be significantly induced by adzuki bean extract in MCF-7 cells. | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | The results indicated that the extract of adzuki bean was able to induce MCF-7 cell growth with a maximum at 100 microg x mL(-1). | |
| Cell line/ mice model | MCF-7 | |
| Additional information | Ethanol extract of adzuki bean has the estrogen-like activities through the estrogen response pathway. | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:525291-1 | |
| Safety | NA |