Phytochemical Name : Adiantum capillus veneris (ACV) extract

Properties Information
PhytoCAT-ID PhytoCAT-256
Phytochemical name or plant extracts Adiantum capillus veneris (ACV) extract
PMID 30194562
Literature evidence Plant products with potential anticancer activities have become a vital source of novel agents in treating cancer.
IUPAC name NA
Phytochemicals’ class or type of plant extracts Methanolic extract and gold nanoparticles
Source of phytochemicals or plant Extracts Adiantum capillus
Geographical availability Afghanistan, Alabama, Albania, Algeria, Angola, Arizona, Arkansas, Assam, Azores, Bahamas, Baleares, Bangladesh, Belize, Botswana, Brazil North, Brazil Northeast, Brazil South, Brazil Southeast, British Columbia, Bulgaria, California, Cambodia, Canary Is., Cape Provinces, Cape Verde, Chad, Chile Central, Chile North, China North-Central, China South-Central, China Southeast, Colorado, Comoros, Corse, Cuba, Cyprus, Djibouti, East Himalaya, Egypt, Ethiopia, Fiji, Florida, France, Free State, Georgia, Great Britain, Greece, Guatemala, Gulf States, Haiti, Hawaii, Honduras, India, Iran, Iraq, Ireland, Italy, Jamaica, Japan, Kazakhstan, Kentucky, Kenya, Korea, Kriti, Krym, KwaZulu-Natal, Laos, Lebanon-Syria, Lesotho, Lesser Sunda Is., Libya, Louisiana, Madagascar, Madeira, Malawi, Malaya, Mali, Maryland, Mauritania, Mauritius, Mexico Central, Mexico Gulf, Mexico Northeast, Mexico Northwest, Mexico Southeast, Mexico Southwest, Mississippi, Missouri, Morocco, Mozambique, Myanmar, Namibia, Nansei-shoto, Nepal, Nevada, New Caledonia, New Mexico, New South Wales, New York, Niger, Nigeria, North Carolina, North Caucasus, Northern Territory, Ohio, Oklahoma, Oman, Pakistan, Palestine, Peru, Philippines, Portugal, Puerto Rico, Queensland, Rodrigues, Réunion, Samoa, Sardegna, Saudi Arabia, Sicilia, Sinai, Society Is., Socotra, Somalia, South Australia, South Carolina, South Dakota, Spain, Sri Lanka, Sudan, Swaziland, Switzerland, Tadzhikistan, Taiwan, Tanzania, Tennessee, Texas, Thailand, Tibet, Tonga, Transcaucasus, Trinidad-Tobago, Tubuai Is., Tunisia, Turkey, Turkey-in-Europe, Uganda, Utah, Uzbekistan, Venezuela, Victoria, Vietnam, Virginia, West Himalaya, Western Australia, Windward Is., Yemen, Yugoslavia, Zambia, Zaïre, Zimbabwe
Plant parts NA
Other cancers Breast cancer
Target gene or protein Bcl-2, Cyclin D1
Gene or Protein evidence By using docking analysis, we also showed that phytol and eicosapentaenoic acid present in ACV and PQ interact with Bcl2 and cyclin D1.
Target pathways NA
IC50 NA
Potency These findings demonstrate that ACV and PQ possess anticancer activities by modulating proteins involved in cell cycle and apoptosis. ACV and PQ that effectively modulate various oncogenic molecules can be used as promising agent for cancer therapy.
Cell line/ mice model MCF-7, BT47
Additional information  NA
PubChem ID NA
Additional PMIDs NA
Additional sources of information https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:325030-2
Safety NA