| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1222 | |
| Phytochemical name or plant extracts | Adenium obesum extract | |
| PMID | 30899170 | |
| Literature evidence | Further, apoptosis and DNA damaging potential of seeds ethanolic extract was analyzed by applying multiple sub-lethal concentrations and durations. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Ethanolic extract | |
| Source of phytochemicals or plant Extracts | Adenium obesum | |
| Geographical availability | Benin, Burkina, Burundi, Cameroon, Chad, Ethiopia, Ghana, Guinea, Guinea-Bissau, Ivory Coast, Kenya, Mali, Mauritania, Niger, Nigeria, Oman, Saudi Arabia, Senegal, Socotra, Somalia, Sudan, Tanzania, Togo, Uganda, Yemen | |
| Plant parts | Leaves, Fruits and Seeds | |
| Other cancers | Breast cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 337 mg/mL against MCF-7 | |
| Potency | This was supported by translocation of PS to outer surface of PM (Fadok et al., 1998) under microscopy, the DNA damage (Nagata, 2000) induced in comet assay also clearly suggest that the seed extract has therapeutic value against cancer cells. | |
| Cell line/ mice model | MCF-7 | |
| Additional information | NA | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:76369-1 | |
| Safety | NA |