Phytochemical Name : Acetoxyscirpendiol

Properties Information
PhytoCAT-ID PhytoCAT-1552
Phytochemical name or plant extracts Acetoxyscirpendiol
PMID 12520168
Literature evidence Taken together, these results strongly indicate that MPT contains potential antitumor components which might exert their action by modulating cell cycle-related genes such as cyclin C and Mad-1 in MCF-7.
IUPAC name NA
Phytochemicals’ class or type of plant extracts Diterpenoid
Source of phytochemicals or plant Extracts Paecilomyces tenuipes
Geographical availability NA
Plant parts NA
Other cancers Breast cancer
Target gene or protein Cyclin C, Mad-1
Gene or Protein evidence MPT contains potential antitumor components which might exert their action by modulating cell cycle-related genes such as cyclin C and Mad-1 in MCF-7.
Target pathways NA
IC50 NA
Potency NA
Cell line/ mice model MCF-7
Additional information  In terms of Mad-1 expression in cells treated with ASD, the level of Mad-1 expression increased up to 2.5 folds by MPT treatment. Cyclin C expression was compared with non-treated cells in various cell lines.
PubChem ID NA
Additional PMIDs NA
Additional sources of information NA
Safety NA