Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-1552 | |
Phytochemical name or plant extracts | Acetoxyscirpendiol | |
PMID | 12520168 | |
Literature evidence | Taken together, these results strongly indicate that MPT contains potential antitumor components which might exert their action by modulating cell cycle-related genes such as cyclin C and Mad-1 in MCF-7. | |
IUPAC name | NA | |
Phytochemicals’ class or type of plant extracts | Diterpenoid | |
Source of phytochemicals or plant Extracts | Paecilomyces tenuipes | |
Geographical availability | NA | |
Plant parts | NA | |
Other cancers | Breast cancer | |
Target gene or protein | Cyclin C, Mad-1 | |
Gene or Protein evidence | MPT contains potential antitumor components which might exert their action by modulating cell cycle-related genes such as cyclin C and Mad-1 in MCF-7. | |
Target pathways | NA | |
IC50 | NA | |
Potency | NA | |
Cell line/ mice model | MCF-7 | |
Additional information | In terms of Mad-1 expression in cells treated with ASD, the level of Mad-1 expression increased up to 2.5 folds by MPT treatment. Cyclin C expression was compared with non-treated cells in various cell lines. | |
PubChem ID | NA | |
Additional PMIDs | NA | |
Additional sources of information | NA | |
Safety | NA |