| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1378 | |
| Phytochemical name or plant extracts | 9-methoxy-camptothecin | |
| PMID | 18596662 | |
| Literature evidence | Among them, compound 1 exhibited significant cytotoxicity against these cancer cell lines, with IC(50) of 0.24-6.57 microM. | |
| IUPAC name | 19-ethyl-19-hydroxy-7-methoxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione | |
| Phytochemicals’ class or type of plant extracts | Alkaloid | |
| Source of phytochemicals or plant Extracts | Nothapodytes foetida | |
| Geographical availability | Assam, Cambodia, East Himalaya, India, Myanmar, Nansei-shoto, Philippines, Sri Lanka, Sumatera, Taiwan, Thailand, Vietnam | |
| Plant parts | Seeds | |
| Other cancers | Breast cancer, Liver cancer, Lung cancer, Squamous cancer, Liver cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 0.37 µM against MCF-7 1.88 µM against MDA-MB-231 | |
| Potency | NA | |
| Cell line/ mice model | HepG2, Hep3B, MDA-MB- 231, MCF-7, A549, and Ca9-22 | |
| Additional information | NA | |
| PubChem ID | 494089 | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:77183920-1 | |
| Safety | NA |