Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-1377 | |
Phytochemical name or plant extracts | 9-methoxy-18,19-dehydrocamptothecin | |
PMID | 18596662 | |
Literature evidence | Among them, compound 1 exhibited significant cytotoxicity against these cancer cell lines, with IC(50) of 0.24-6.57 microM. | |
IUPAC name | NA | |
Phytochemicals’ class or type of plant extracts | Alkaloid | |
Source of phytochemicals or plant Extracts | Nothapodytes foetida | |
Geographical availability | Assam, Cambodia, East Himalaya, India, Myanmar, Nansei-shoto, Philippines, Sri Lanka, Sumatera, Taiwan, Thailand, Vietnam | |
Plant parts | Seeds | |
Other cancers | Breast cancer, Liver cancer, Lung cancer, Squamous cancer, Liver cancer | |
Target gene or protein | NA | |
Gene or Protein evidence | NA | |
Target pathways | NA | |
IC50 | 6.22 µM against MCF-7 6.57 µM against MDA-MB-231 | |
Potency | NA | |
Cell line/ mice model | HepG2, Hep3B, MDA-MB- 231, MCF-7, A549, and Ca9-22 | |
Additional information | NA | |
PubChem ID | NA | |
Additional PMIDs | NA | |
Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:77183920-1 | |
Safety | NA |