Phytochemical Name : 9-methoxy-18,19-dehydrocamptothecin

Properties Information
PhytoCAT-ID PhytoCAT-1377
Phytochemical name or plant extracts 9-methoxy-18,19-dehydrocamptothecin
PMID 18596662
Literature evidence Among them, compound 1 exhibited significant cytotoxicity against these cancer cell lines, with IC(50) of 0.24-6.57 microM.
IUPAC name NA
Phytochemicals’ class or type of plant extracts Alkaloid
Source of phytochemicals or plant Extracts Nothapodytes foetida
Geographical availability Assam, Cambodia, East Himalaya, India, Myanmar, Nansei-shoto, Philippines, Sri Lanka, Sumatera, Taiwan, Thailand, Vietnam
Plant parts Seeds
Other cancers Breast cancer, Liver cancer, Lung cancer, Squamous cancer, Liver cancer
Target gene or protein NA
Gene or Protein evidence NA
Target pathways NA
IC50 6.22 µM against MCF-7 6.57 µM against MDA-MB-231
Potency NA
Cell line/ mice model HepG2, Hep3B, MDA-MB- 231, MCF-7, A549, and Ca9-22
Additional information  NA
PubChem ID NA
Additional PMIDs NA
Additional sources of information https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:77183920-1
Safety NA