| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1819 | |
| Phytochemical name or plant extracts | 9β,13β-epoxy-7-abietene | |
| PMID | 24451247 | |
| Literature evidence | The antioxidant activity was determined by 2,2-diphenyl-1-picryl-hydrazyl (DPPH), β-carotene-linoleic acid system and 2,2'-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) assays. | |
| IUPAC name | (1S,2S,12S)-2,6,6-trimethyl-12-(propan-2-yl)-15-oxatetracyclo[10.2.1.0¹,¹⁰.0²,⁷]pentadec-9-ene | |
| Phytochemicals’ class or type of plant extracts | Diterpene | |
| Source of phytochemicals or plant Extracts | Tetradenia riparia | |
| Geographical availability | Angola, Botswana, KwaZulu-Natal, Malawi, Mozambique, Namibia, Northern Provinces, Swaziland, Zimbabwe | |
| Plant parts | Leaves | |
| Other cancers | Breast cancer, Colon cancer, Leukemia | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | The essential oil and 9β,13β-epoxy-7-abietene showed high cytotoxic potential of the cell lines SF-295 (78.06% and 94.80%, respectively), HCT-8 (85.00% and 86.54%, respectively) and MDA-MB-435 (59.48% and 45.43%, respectively). | |
| Cell line/ mice model | MDA-MB-435, HCT-8, SF-295, HL-60 | |
| Additional information | NA | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:913408-1 | |
| Safety | NA |