Phytochemical Name : 8-methoxydihydrochelerythrine

Properties Information
PhytoCAT-ID PhytoCAT-1308
Phytochemical name or plant extracts 8-methoxydihydrochelerythrine
PMID 25761206
Literature evidence Both compounds indicated significant cytotoxicity against MCF-7 and SF-268 cell lines.
IUPAC name 17,18,20-trimethoxy-21-methyl-5,7-dioxa-21-azapentacyclo[11.8.0.0²,¹?.0?,?.0¹?,¹?]henicosa-1(13),2(10),3,8,11,14,16,18-octaene
Phytochemicals’ class or type of plant extracts Alkaloid
Source of phytochemicals or plant Extracts Macleaya cordata
Geographical availability China North-Central, China South-Central, China Southeast, Japan, Taiwan
Plant parts Fruits
Other cancers Breast cancer, Glioma
Target gene or protein NA
Gene or Protein evidence NA
Target pathways NA
IC50 21.45 µM against MCF-7
Potency Exhibits cytotoxicity against MCF-7 and SF-268 cell lines
Cell line/ mice model MCF-7, SF-269
Additional information  NA
PubChem ID NA
Additional PMIDs NA
Additional sources of information https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:673258-1
Safety NA